Introduction:
Chemical burn due to giant hogweed (Heracleum sosnowskyi) has been reported as a cause of burn injury in the literature. However, there have been no published articles in the literature presenting a course of this kind injury in patients with any kind of immune deficiency.

Aim:
The aim of this review and case report is to raise awareness of phytophotodermatitis and burns caused by plants.

Case study:
We report the case of a 46-year-old man with a full thickness chemical burn on his right pretibial area due to phytophotodermatitis (PPD) following contact with giant hogweed. The patient was diagnosed with HIV and HCV infections in 2006. He is on ARV therapy with a good immunological outcome. At first, the wounds were surgically dressed and a pharmacological procedure was introduced. He was discharged with a recommendation to treat the affected areas with a steroid cream. After almost two years (II.2017) the wound is still in process of healing. The area of open wound decreased by 50% compared to V.2015.

Results and discussion:
Human immunodeficiency virus (HIV), HAART, low CD4 cell count and high incidence of wound infections results in impaired wound healing process in HIV(+) patients. There is a lack of information on burns caused by plants in HIV positive patients, who are put on aggressive ART therapy that may lead to increased photosensitivity of the skin.

Conclusions:
It is crucial to alert all patients from the risk groups to the risk of being in areas with high-dense vegetation in the condition of high sunlight exposure.