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RESEARCH PAPER
Invasive measurement of portal hypertension in the hemodynamics laboratory as an important element of qualification for the treatment of esophageal varices: A single-center experience
1
Department of Cardiology, Voivodal Specialist Hospital in Olsztyn, Poland
2
Department of Cardiology and Internal Medicine, School of Medicine, Collegium Medicum, University of Warmia and Mazury in Olsztyn, Poland
3
Department of Internal Medicine, School of Medicine, Collegium Medicum, University of Warmia and Mazury in Olsztyn, Poland
4
Department of Gastroenterology, Voivodal Specialist Hospital in Olsztyn, Poland
5
Department of Anaesthesiology and Intensive Care, School of Medicine, Collegium Medicum, University of Warmia and Mazury, Olsztyn, Poland
6
Clinical Department of Anaesthesiology and Intensive Care, Voivodal Specialist Hospital in Olsztyn, Poland
7
Emergency Medicine Department, School of Medicine, Collegium Medicum, University of Warmia and Mazury in Olsztyn, Poland
8
Clinical Emergency Department, Voivodal Specialist Hospital in Olsztyn, Poland
9
Department of Invasive Cardiology, Centre of Postgraduate Medical Education, Warsaw, Poland
Submission date: 2020-12-28
Final revision date: 2021-03-30
Acceptance date: 2021-03-30
Online publication date: 2021-04-21
Publication date: 2021-04-21
Corresponding author
Jacek Bil
Voivodal Specialist Hospital, Żołnierska 18, 10-561 Olsztyn, Poland. Tel. +4889 538 64 23.
Voivodal Specialist Hospital, Żołnierska 18, 10-561 Olsztyn, Poland. Tel. +4889 538 64 23.
Pol. Ann. Med. 2021;28(1):57-61
KEYWORDS
TOPICS
ABSTRACT
Introduction:
The measurement of hepatic venous pressure gradient (HVPG) is an essential prognostic factor in subjects with chronic liver disorders.
Aim:
The present study aimed to present the feasibility and applicability of HVPG in the modern hemodynamics laboratory in patients with liver cirrhosis as a stage for qualification in variceal band ligation (VBL).
Material and methods:
We included 78 patients with liver cirrhosis and esophageal varices, who had HVPG measurements taken at the hemodynamics laboratory between January 2015 and January 2019.
Results and discussion:
The mean age was 55.5 ± 10.9 years, and 66.7% were males. The most common cause of liver cirrhosis was alcohol abuse (65.4%), and the most common varices stage was 3 (83.3%). The mean HVPG was 16.3 ± 6.2 mm Hg. In total, 67 (85.9%) patients had HVPG over 10 mm Hg and underwent VBL. No periprocedural complications were observed. At 12 months, recurrent hospitalizations were observed in 67 (85.9%), 5 (6.4%)had cirrhosis-related bleeding episodes, and 4 (5.1%) patients died.
Conclusions:
HVPG measurement is a feasible, safe and reproducible procedure that provides valuable diagnostic/prognostic information and helps make therapeutic decisions. This procedure can be done quickly in the modern hemodynamics laboratory.
The measurement of hepatic venous pressure gradient (HVPG) is an essential prognostic factor in subjects with chronic liver disorders.
Aim:
The present study aimed to present the feasibility and applicability of HVPG in the modern hemodynamics laboratory in patients with liver cirrhosis as a stage for qualification in variceal band ligation (VBL).
Material and methods:
We included 78 patients with liver cirrhosis and esophageal varices, who had HVPG measurements taken at the hemodynamics laboratory between January 2015 and January 2019.
Results and discussion:
The mean age was 55.5 ± 10.9 years, and 66.7% were males. The most common cause of liver cirrhosis was alcohol abuse (65.4%), and the most common varices stage was 3 (83.3%). The mean HVPG was 16.3 ± 6.2 mm Hg. In total, 67 (85.9%) patients had HVPG over 10 mm Hg and underwent VBL. No periprocedural complications were observed. At 12 months, recurrent hospitalizations were observed in 67 (85.9%), 5 (6.4%)had cirrhosis-related bleeding episodes, and 4 (5.1%) patients died.
Conclusions:
HVPG measurement is a feasible, safe and reproducible procedure that provides valuable diagnostic/prognostic information and helps make therapeutic decisions. This procedure can be done quickly in the modern hemodynamics laboratory.
FUNDING
None declared.
CONFLICT OF INTEREST
None declared.
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